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    Can you provide an example of the correlation between the stability of a drug and its pH value?
    2024-10-11   Sichen Instrument    473

    Of course, the following are examples of how the stability of some drugs is related to their pH value:

    Vitamin C: Vitamin C is relatively stable under acidic conditions, but it is prone to oxidation reactions under alkaline conditions. Therefore, in pharmaceutical formulations, the pH value of vitamin C is usually controlled within the acidic range to maintain its stability and effectiveness.

    Aspirin: Aspirin is relatively stable under acidic conditions, but it is prone to hydrolysis under alkaline conditions. Therefore, in pharmaceutical formulations, the pH value of aspirin is usually controlled within the acidic range to maintain its stability and effectiveness.

    Penicillin: Penicillin is relatively stable under alkaline conditions, but is prone to acid hydrolysis reactions under acidic conditions. Therefore, in pharmaceutical formulations, the pH value of penicillin is usually controlled within the alkaline range to maintain its stability and effectiveness.

    These examples demonstrate that the stability of drugs is closely related to their pH value. By controlling the pH value of drugs, their stability and shelf life can be extended, ensuring their safety and efficacy.

    How to control the pH value? We recommend a patented product - pH automatic control liquid addition system

    Instrument Overview

    This system is a new type of automated control system that integrates pH value online display, measurement, and automatic adjustment of acid/alkali solution. Widely used in places where pH value needs to be controlled and adjusted, such as laboratory researchers monitoring and controlling the acidity and alkalinity of solutions in various reaction vessels, reaction tanks, biochemical containers, catalytic fields, and bioreactors. This system is the latest third-generation high-precision pH automatic control system developed by the R&D team of Changsha Sichen Instrument, and is used in laboratories of universities and research institutes; Carefully designed and manufactured by domestic and foreign R&D enterprises and R&D production departments in biopharmaceuticals, life sciences, and other fields. And it has completely independent intellectual property rights, obtaining one national invention patent (ZL201410349779.8) and multiple utility model patents (ZL201721373766.X); ZL 201420406067.0; ZL201420406055.8. The whole machine adopts PLC control and is connected with a customized peristaltic pump to automatically adjust the preset pH value of the solution in the container by adding acid or alkali. It is an ideal pH monitoring and automatic control system for laboratories such as catalysis, pharmaceuticals, chemical engineering, electroplating, biochemistry, biological fermentation, plant extract workshops, scientific institutes, or small production test sites.


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